Grag, Ramaraj P N, and Palekar: Traumatic cyst of the mandible with fibrous invasion: A rare case variant


Introduction

Traumatic bone cyst (TBC) was described first by Lucas and Blum in 1929 who coined the term “Traumatic bone cyst”. It is defined as a “non-neoplastic intraosseous pseudocyst devoid of epithelial lining” by the World Health Organization (WHO). It has been referred by different terminologies like a simple bone cyst, hemorrhagic cyst, idiopathic bone cavity, progressive bone cavity, and solitary unicameral bone cyst. Many theories describe the etiology but no definite etiology has been determined. The trauma-hemorrhage theory proposed trauma followed by degeneration of clot to be responsible for the development of the cyst. But most cases of traumatic cyst have no history of trauma to be associated. The factors suggested to be associated are low- grade infection, intraosseous vascular abnormalities, degeneration of bone tumors, local alteration of bone metabolism, and trauma. The traumatic bone cyst has also been associated with representing resolving fibro-osseous lesions.

A traumatic bone cyst is usually asymptomatic and hence diagnosed on a routine radiograph. TBC may be lined by fibrous connective tissue without epithelium.

Our case report discusses a rare variant of TBC associated with fibrous hypertrophy.

Case Report

A 19-year-old male patient had reported to the department of orthodontics & dentofacial orthopedics of KVG Dental College with the chief complaint of malaligned teeth since the past 5 years. The patient was then referred to our department of Oral & Maxillofacial Surgery of KVG Dental College for evaluation of an asymptomatic unilocular radiolucency of the mandibular anterior region which was found while routine radiographic screening for orthodontic treatment.

When the patient reported to us, with an of the history of dental extraction 7 months back with respect to 47,43,37. On local examination, a face was bilaterally symmetrical (Figure 1). Skin, nose, eyes, ears & lips looked normal. Mouth opening was adequate. There was no loss of sensation. TMJ bilaterally palpable with no associative abnormality and no lymph nodes were palpable.

Figure 1

Extraoral examination

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Figure 2

Intraoral examination

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On intraoral examination, the buccal and lingual mucosa, palate, tongue (both dorsal and ventral surface), floor of mouth were normal (Figure 2). Periodontal status was found to be fair. No swelling or draining sinus was noted. Missing tooth were 13,14,15,37,32,42,47. On palpation, all the inspector findings were confirmed but no abnormality could be detected.

On radiographic examination, panoramic review a unilocular well defined radiolucent seen with scalloped border measuring about 6 x 3 cm extending from the mesial root of lower right molar to mesial root of the lower left premolar. Missing 37,47 and congenitally missing 32 and 42. Impacted 13 and 14(Figure 3). On further investigation computer tomography was done, a coronal section of CT(Figure 4) relieved radiolucent lesion with a scalloped border. Mandibular canal is placed buccally on the right side and left side mandibular canal is on centrally placed, in sagittal section (Figure 5). Presence of lesion with scalloped margin extending from the mesial root of 46 till mesial root of 35 with thinning of lingual cortical plate and expansion of buccal cortical plate. Axial section(Figure 6) on maxilla impacted reveals 13 and right mandibular canal pushed buccally mandibular nerve length on the left side is 11.85 and width is 21.97 and on the right side is 12.15 and width is 30.49.

Figure 3

Orthopantomogram

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Figure 4

CT scan coronal section, radiolucent with scalloped border

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Figure 5

CT scan sagittal section thinning of lingual cortical plate

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Figure 6

CT scan axial section, maxillary 13 impacted

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The patient was provisionally diagnosed with Odontogenic Keratocyst (OKC).

A fine needle aspirated was showed serous with bloody fluid(Figure 7). Histopathology report revealed protein estimate to be 5.8g/dl and diagnosis as odontogenic keratocyst.

Figure 7

Fine needle aspiration cytology

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A biopsy was been taken with a removal of 1 cm2 of bone by postage stamp method. The biopsy report showed the presence of extravasated RBC with both acute and chronic inflammatory cells small fragments of fibro cellular connective tissue suggestive of Traumatic bone cyst (TBC). The treatment plan was cyst enucleation under general anesthesia. A patient was kept for a regular follow up.

Discussion

Traumatic bone cysts are generally detected in patients of the second and third decade of life.1 The lesion remains asymptomatic and it is mostly identified during routine radiographic examination.2 Traumatic bone cyst occurs in the mandible predominantly in the posterior region, usually extending from canine to third molar region.3 However, in our case, the lesion was located bilaterally in the mandibular anterior region extending from central incisor to the distal aspect of the premolar. Both traumas insufficient to fracture a healthy bone and iatrogenic trauma induced by either tooth extraction or orthodontic treatment have been implicated as inciting factors in traumatic bone cyst formation.

In literature, irrespective of the location of the traumatic bone cyst, the etiology remains unclear. Among the many theories, three predominate ones are: (1) an abnormality of osseous growth, (2) a degenerating tumoral process, and (3) a particular factor triggering hemorrhagic trauma.4 In Howe's series,5 over one-half of the patients had a definite history of trauma and the author noted that the severity of the trauma was a striking feature.

In some case reports of TBCs, the authors have been discussed the possibility of the performed dental extractions may be responsible for the trauma factor in their cases. Two of these extractions were considered difficult, whereas none of them was surgical.5 In our case-patient underwent extraction with respect to 47,43,37 since 7 month back in which postoperative healing was uneventful. Blum and Toma believed that there must also be a predisposing idiosyncratic factor in the pathogenesis of TBC, such as a peculiarity of the vessel wall or abnormal coagulation of the blood.6

The radiolucency characterizes the radiographic features with well-defined irregular or scalloped borders. Involvement of the radiolucency into the interdental bone spaces presents a lobular, scalloped or festooned pattern.7 The histology of traumatic bone cysts reveals only a connective tissue membrane lining the pathologic cavity, characteristic of pseudocysts. Cholesterol crystals, hemorrhagic foci, and osteoclasts may be found.8 In our case, FNAC report relieved as smear shows predominantly inflammatory cells, few epithelial cells and RBC flecks of keratin is also seen and biopsy relieved loose myxomatous connective tissue surrounding a large area of extravasated RBC’s with both acute and chronic inflammatory cells and small fragments of fibro cellular connective tissue.

Therefore, traumatic bone cysts should be part of the differential diagnosis of maxillary radiolucent lesions together with dentigerous cysts, keratocystic odontogenic tumors, ameloblastomas, odontogenic myxomas, aneurismatic bone cysts, focal osteoporotic bone marrow defect, intraosseous vascular malformations, and central giant cell lesions.

The treatment plan of curettage should be performed surgically as it induces bleeding and further osseous regeneration.

Source of Funding

None.

Conflict of Interest

The authors declare no conflict of interest.

References

1 

G L Freedman M B Beigleman The traumatic bone cyst: A new dimensionOral Surg, Oral Med, Oral Pathol1985596616810.1016/0030-4220(85)90191-4

2 

C Lucas T Blum Do all cysts of the jaws originate from the dental systemJ Am Dent Assoc192916464761

3 

P A Toller Radioactive isotope and other investigations in a case of haemorrhagic cyst of the mandibleBr J Oral Surg19642869310.1016/s0007-117x(64)80019-6

4 

L K S Kumar N Kurien K A Thaha K A Traumatic bone cyst of mandibleJ Maxillofac Oral Surg201514246675

5 

G L Howe Haemorrhagic cysts’ of the mandible—IBr J Oral Surg19653557610.1016/s0007-117x(65)80008-7

6 

T Blum Additional report on traumatic bone cystsOral Surg Oral Med Oral Pathol19558991739

7 

Y Suei A Taguchi T Nagasaki K Tanimoto Radiographic findings and prognosis of simple bone cysts of the jawsDentomaxillofac Radiol2010392657210.1259/dmfr/54872008

8 

P R S Martins-Filho T de S Santos S Araújo V L C de Araújo J S Santos E S de SAndrade, Traumatic bone cyst of the mandible: a review of 26 casesBraz J Otorhinolaryngol20127821621



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https://doi.org/10.18231/j.ijohd.2020.063


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