Original Article
Author Details :
Volume : 10, Issue : 2, Year : 2024
Article Page : 95-100
https://doi.org/10.18231/j.ijohd.2024.020
Abstract
Background: Mouthwashes are used routinely as adjunct to scaling and root planing. Chlorhexidine mouthwash is known as gold standard while Listerine is a widely used essential oil mouthwash. This study was done to evaluate and compare the genotoxic effect of Listerine with Chlorhexidine mouthwash on buccal cells.
Materials and Methods: It was a parallel design study with 20 participants in each group (Group 1: Chlorhexidine mouthwash and Group 2: Listerine mouthwash). Gingival index was recorded and buccal cells scraping were taken at baseline and 3 weeks after use of respective mouthwashes. The buccal cells were assessed for cytotoxicity using micronuclei test (under microscope at 100 x magnification) using Papanicolaou Stain.
Results: There was a statistically significant reduction seen in gingival index from baseline to 3 weeks in both the groups (p< 0>
Conclusion: After a 3 weeks exposure, Listerine mouthwash showed less cytotoxicity on buccal cells as compared to Chlorhexidine mouthwash.
Keywords: Alcoholbased Mouthwash, Chlorhexidine, Cytotoxicity, Listerine, Mouthwash, Papanicolaou stains.
How to cite : Shah S, Rai J, Shah M, Shah N, Comparative analysis of chlorhexidine and listerine mouthwashes on buccal cell health: A clinical and cytological investigation. Int J Oral Health Dent 2024;10(2):95-100
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Received : 01-03-2024
Accepted : 24-04-2024
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